Targets / Kinase / BIKE

BMP2 inducible kinase (BIKE)

Target Class
Kinase
Family
Other
Official Symbol
BMP2K
Entrez Gene ID
55589
Species
Human
Accession Number
NP_060063.2
Alias Names
BIKE; BMP-2-inducible protein kinase; BMP2 inducible kinase
Background
This gene is the human homolog of mouse BMP-2-inducible kinase. Bone morphogenic proteins (BMPs) play a key role in skeletal development and patterning. Expression of the mouse gene is increased during BMP-2 induced differentiation and the gene product is a putative serine/threonine protein kinase containing a nuclear localization signal. Therefore, the protein encoded by this human homolog is thought to be a protein kinase with a putative regulatory role in attenuating the program of osteoblast differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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