Targets / Kinase / BLK
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B lymphoid tyrosine kinase (BLK)

Target Class
Kinase
Family
Cytosolic tyrosine kinase
Official Symbol
BLK
Species
Human
Accession Number
NM_001715.2
Alias Names
B lymphoid tyrosine kinase; BLK nonreceptor tyrosine kinase; MODY11; b lymphocyte kinase; p55-Blk; tyrosine-protein kinase Blk
Background
This gene encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors. [provided by RefSeq, Aug 2010]
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Solution Portfolio

Related Group Members: Cytosolic tyrosine kinase
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Cell Lines
Assay Measures Background Species Cell Line
Receptor Phosphorylation U2OS Human 93-0882C3
Intracellular Binding HEK 293 96-0044C1
Ready to Use eXpress Kits
Assay Measures Background Species Assay Kit
Receptor Phosphorylation U2OS Human 93-0882E3CP16M
Receptor Phosphorylation U2OS Human 93-0882E3CP16L
Intracellular Binding HEK 293 96-0044E1CP0M
Intracellular Binding HEK 293 96-0044E1CP0L
LeadHunter Screening & Profiling Services
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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