Targets / Kinase / DYRK2

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 (DYRK2)

Target Class
Kinase
Family
CMGC
Official Symbol
DYRK2
Entrez Gene ID
8445
Species
Human
Accession Number
NP_003574.1
Alias Names
dual specificity tyrosine-phosphorylation-regulated kinase 2; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
Background
DYRK2 belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and/or development. The family is defined by structural similarity of their kinase domains and their capability to autophosphorylate on tyrosine residues. DYRK2 has demonstrated tyrosine autophosphorylation and catalyzed phosphorylation of histones H3 and H2B in vitro. Two isoforms of DYRK2 have been isolated. The predominant isoform, isoform 1, lacks a 5' terminal insert. [provided by RefSeq, Jul 2008]
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Related Group Members: CMGC
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