Targets / Kinase / MAP3K15

mitogen-activated protein kinase kinase kinase 15 (MAP3K15)

Target Class
Kinase
Family
STE
Official Symbol
MAP3K15
Entrez Gene ID
389840
Species
Human
Accession Number
NP_001001671.3
Alias Names
ASK3; MAPK/ERK kinase kinase 15; MEK kinase 15; MEKK 15; apoptosis signal-regulating kinase 3; bA723P2.3; mitogen-activated protein kinase kinase kinase 15
Background
The protein encoded by this gene is a member of the mitogen-activated protein kinase (MAPK) family. These family members function in a protein kinase signal transduction cascade, where an activated MAPK kinase kinase (MAP3K) phosphorylates and activates a specific MAPK kinase (MAP2K), which then activates a specific MAPK. This MAP3K protein plays an essential role in apoptotic cell death triggered by cellular stresses. [provided by RefSeq, Jul 2010]
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Related Group Members: STE
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