Biological Information | |
---|---|
Background Information: | NEK11 is a protein kinase which plays an important role in the G2/M checkpoint response to DNA damage. Controls degradation of CDC25A by directly phosphorylating it on residues whose phosphorylation is required for BTRC-mediated polyubiquitination and degradation. |
Target Class: | Kinase |
Accession Number: | NM_024800.3; NM_145910.2 |
Target Name: | NEK11 |
Target Aliases: | NEK11, FLJ23495 |
Target Species: | Human |
Usage | |
Product Type: | Enzymes |
Application: | Drug Discovery & Development |
Storage Conditions: | 6 months at -70°C |
Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
Datasheets
14-700x Datasheet
View Document