mitogen-activated protein kinase 13 (p38-delta)

Target Class
Kinase
Family
CMGC
Official Symbol
MAPK13
Entrez Gene ID
5603
Species
Human
Accession Number
NP_002745.1
Alias Names
MAP kinase 13; MAP kinase p38 delta; MAPK 13; PRKM13; SAPK4; mitogen-activated protein kinase 13; mitogen-activated protein kinase p38 delta; p38delta; stress-activated protein kinase 4
Background
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and cellular stress. MAP kinase kinases 3, and 6 can phosphorylate and activate this kinase. Transcription factor ATF2, and microtubule dynamics regulator stathmin have been shown to be the substrates of this kinase. [provided by RefSeq, Jul 2008]
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Solution Portfolio

Related Group Members: CMGC
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KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
Available