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p21 protein (Cdc42/Rac)-activated kinase 2 (PAK2)

Target Class
Kinase
Family
STE
Official Symbol
PAK2
Entrez Gene ID
5062
Species
Human
Accession Number
AAA65442.1
Alias Names
PAK-2; PAK65; PAKgamma; S6/H4 kinase; gamma-PAK; p21 (CDKN1A)-activated kinase 2; p21 protein (Cdc42/Rac)-activated kinase 2; p21-activated kinase 2; p58; serine/threonine-protein kinase PAK 2
Background
The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. [provided by RefSeq, Jul 2008]
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Related Group Members: STE
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KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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