Targets / Kinase / PIP5K2B

phosphatidylinositol-5-phosphate 4-kinase, type II, beta (PIP5K2B)

Target Class
Kinase
Family
Lipid
Official Symbol
PIP4K2B
Entrez Gene ID
8396
Species
Human
Accession Number
NP_003550.1
Alias Names
1-phosphatidylinositol-4-phosphate kinase; 1-phosphatidylinositol-5-phosphate 4-kinase 2-beta; PI(5)P 4-kinase type II beta; PI5P4KB; PIP4KII-beta; PIP5K2B; PIP5KIIB; PIP5KIIbeta; PTDINS(4)P-5-kinase; diphosphoinositide kinase 2-beta; phosphatidylinositol-4-phosphate 5-kinase, type II, beta; phosphatidylinositol-5-phosphate 4-kinase type-2 beta; phosphatidylinositol-5-phosphate 4-kinase, type II, beta; ptdIns(5)P-4-kinase isoform 2-beta
Background
The protein encoded by this gene catalyzes the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family. The encoded protein sequence does not show similarity to other kinases, but the protein does exhibit kinase activity. Additionally, the encoded protein interacts with p55 TNF receptor. [provided by RefSeq, Jul 2008]
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Related Group Members: Lipid
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