| June 17, 2020 |
Webinar: Simple Signaling Reporter Assays – Easily Quantify Activation & Inhibition of Cellular Pathways - 30 min.
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| February 26, 2020 |
Webinar: Protein Degradation (PROTACs/CRISPR) Assays - 60 min.
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| October 9, 2019 |
Webinar: Establishing Qualified Bioassays for Checkpoint Receptors to Implement in QC Lot Release: Case Studies on PD-1 and SIRPα - 60 min.
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| May 9, 2018 |
Webinar: Accelerate Biologics and Biosimilars Development: Case Studies Implementing Robust and Simple Potency Bioassays - 60 min.
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| December 6, 2017 |
Webinar: Application of β-Arrestin Assays to the Orphan GPCR World - 30 min.
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| November 29, 2017 |
Webinar: Implementing ADCC assays in QC: When donor variability isn’t an option - 55 min.
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| November 1, 2017 |
Webinar: How to Accelerate Your Biotherapeutic Development with Cell-Based Assay Services - 40 min.
What will be covered?
- How PathHunter services save development time compared to in-house assays
- Screening and profiling biologics with highly specific and sensitive assays that produce robust and reproducible results
- Example data from marketed drugs, like Pembrolizumab and Nivolumab, using these cell-based assays
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| September 20, 2017 |
Webinar: Create Your Own Cell-Based Assays to Study Receptor Tyrosine Kinase Function - 30 min.
What will be covered?
- RTK biology and drug discovery importance
- Tools needed to create your own RTK cell lines and assays
- Experimental design and workflows
- Applications of RTK and related cell-based assays
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| August 16, 2017 |
Webinar: Discovery of Bacterial Effectors in the Human Microbiome and Isolation of a GPCR G2A/GPR132 Agonist - 30 min.
What will be covered?
- The role of GPCRs in regulating host-microbial interactions
- How to identify microbial metabolites that modulate GPCR functions
- A case study on defining host-microbial interaction and therapeutic potential of N-acyl amides, bacterial metabolites that activate GPR132/G2A
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| June 28, 2017 |
BIOtech Japan 2017
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| June 27, 2017 |
Webinar: Driving Robust ADCC and T Cell Redirection with KILR® CD16 Effector Cells - 55 min.
What will be covered?
- Eliminating donor variability in cytotoxicity assays with single donor-derived primary human KILR CD16 Effector Cells
- Better analysis of antibody’s cytotoxicity profile with better Hill Slopes and higher S:B compared to PBMCs
- Faster assessment of redirected T cell-mediated cytotoxicity with rapid killing kinetics of the CD16 Effector cells
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| June 27, 2017 |
Drug Repositioning, Repurposing and Rescue Conference 2017
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| May 18, 2017 |
Create Your Own Cellular Target Engagement Assay - 30 min.
What will be covered?
- Overview of compound-target engagement
- Tools and workflow to create your own cell-based target engagement assay
- Applications of InCELL Pulse assays
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| May 1, 2017 |
PEGS Summit 2017
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| April 19, 2017 |
Webinar: Combining Target-Based and Phenotypic Discovery Assays for Drug Repurposing - 40 min.
What will be covered?
- Using phenotypic profiling to characterize clinically successful drugs for a given indication
- Combining target-based and phenotypic data to prioritize drugs for repurposing
- Understanding how multi-targeted kinases can be pivoted towards new indications
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| April 5, 2017 |
Webinar: From Chemistry to Clinic: Discovery of Biased Apelin Receptor Agonists and Action in the Cardiovascular System - 55 min.
What will be covered?
- Role of GPCRs in human cardiovascular system
- Strategies for exploiting orphan GPCRs recently paired with endogenous ligands illustrated by Apelin and Elabela/Toddler
- Identifying biased agonists using pharmacologically-relevant functional cell based assays
- Validating assays and minimizing inter-assay variation
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| March 29, 2017 |
Webinar: Creating Cellular Target Engagement Assays for Diverse Kinases Using InCELL Pulse™ - 30 min.
What will be covered?
- Overview of compound-target engagement and InCELL Pulse platform
- Kinase drug discovery importance
- Tools and workflow needed to create your own target engagement assay
- Validation data showing several examples of diverse kinases
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| March 14, 2017 |
Immune Checkpoint Inhibitors 2017
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| March 9, 2017 |
Webinar: Mu Opioid Receptor Splicing and Signaling: Another Dimension of GPCR Function - 55 min.
What will be covered?
- Overview of the mu opioid receptor signaling
- GPCR splicing, using OPRM1 as an example
- Region and cell specific splicing
- Functional consequences of 5’ splicing
- Functional consequences of 3’ splicing
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| March 8, 2017 |
US Bioassay Conference (BEBPA) 2017
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| February 1, 2017 |
Webinar: Unlocking GPCRs for Oncology - 35 min.
What will be covered?
- Opportunities and challenges for targeting GPCRs in oncology
- Examples of GPCR-targeting investigational therapies for oncology
- Imipridones, selective GPCR-targeting small molecules, that are in preclinical and clinical development for oncology
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| December 7, 2016 |
Webinar: The Interplay of Kinase Broad Profiling and Phenotypic Screening - 60 min.
What will be covered?
- Learn about the significance of kinase broad profiling and phenotypic screening on early kinase drug discovery
- Learn how to design a kinase inhibitor broad profiling project and how the chemo-bioinformatic analysis can impact target deconvolution after phenotypic screening
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| November 30, 2016 |
Webinar: Create Your Own InCELL Pulse™ Cellular Compound-Target Engagement Assay - 60 min.
What will be covered?
- Overview of compound-target engagement
- Tools needed to create your own target engagement assay
- Experimental design and workflow
- Applications of InCELL Pulse assays
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| November 9, 2016 |
Webinar: Duplexed Screening of GPCRs to Measure Calcium and β-Arrestin - 60 min.
What will be covered?
- Screening approaches for GPCR drug discovery
- Creating a duplexed assay to monitor calcium and β-arrestin in a single well
- Determine potential bias for various drugs and define potency ranking
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| October 26, 2016 |
Webinar: Target to Phenotype: Tools to Accelerate Your Immuno-Oncology Drug Pipeline - 60 min.
What will be covered?
- Challenges in immuno-oncology drug development
- Tools to expedite and simplify any immuno-oncology drug development pipeline
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| September 30, 2016 |
Webinar: Immuno-Oncology Drug Development: Profiling Immunomodulatory Biologics and Compounds in Human Primary Cell-Based Oncology Models - 60 min.
What will be covered?
- Overview of the BioMAP® immuno-oncology/oncology systems
- Information BioMAP iOnc studies provide
- Host stromal/vascular - tumor microenvironment biology
- Case studies of profiling Ab therapies (anti-PD-1, anti-CTLA-4, etc.) and preclinical compounds
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| August 10, 2016 |
Webinar: New Tricks for Old Drugs: An Unbiased Phenotypic Approach to Drug Repurposing - 40 min.
What will be covered?
- Overview of the BioMAP Diversity PLUS phenotypic screening platform's modeling of broad human tissue and disease biology
- Details of how Diversity PLUS profiling guides new indications for marketed drugs and pre-clinical candidates
- Examples highlighting how this technology is used to support repositioning of approved drugs for alternate indications
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| May 25, 2016 |
Webinar: A Phenotypic Platform for Characterization of Drug Safety Mechanisms in Human Primary Cell Disease Models - 40 min.
What will be covered?
- How to maximize knowledge of your compounds using the BioMAP® Diversity PLUS™ panel of human primary cells systems
- How to understand mechanism classification analysis and toxicity signatures
- A case study on discovery of a mechanism-based novel signature for skin irritation
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| November 10, 2013 |
2013 AAPS Annual Meeting and Exposition
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| October 28, 2013 |
FAST 2013: Functional Analysis & Screening Technologies
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| October 17, 2013 |
14th Annual G Protein-Coupled Receptor (GPCR) Retreat
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| September 24, 2013 |
11th Annual Discovery on Target
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| July 23, 2013 |
EpiCongress
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| July 8, 2013 |
8th Protein Kinases in Drug Discovery
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| June 17, 2013 |
Next-Gen Kinase Inhibitors
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| June 5, 2013 |
World Pharma Congress
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| May 7, 2013 |
Merck Technology Symposium
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| April 30, 2013 |
CHI - PEG Summit
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| April 25, 2013 |
ASPET - 4th GPCR Colloquium
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| April 16, 2013 |
CHI - Drug Discovery Chemistry
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| April 6, 2013 |
American Association for Cancer Research
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| March 20, 2013 |
Epigenetic Marks and Cancer Drugs
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| March 20, 2013 |
GTC: 2nd Inflammatory and Immunological BioMarkers Meeting
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| March 19, 2013 |
ELRIG - Research & Innovation
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| March 14, 2013 |
SGC
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| March 11, 2013 |
Society of Toxicology
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| March 7, 2013 |
The 1st International Congress on Controversies in Personalized Oncology
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| February 25, 2013 |
3rd Ubiquitin Research and Drug Discovery
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| January 14, 2013 |
2013 SLAS Conference & Exhibition
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| January 13, 2013 |
SLAS Satellite Symposium at the Sanford-Burnham Medical Research Institute in Lake Nona
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| October 17, 2012 |
GPCR Retreat
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| October 13, 2012 |
Society for Neuroscience (SfN)
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| October 4, 2012 |
DiscoveRx Technology Symposium
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| October 1, 2012 |
CHI-DOT 2012
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| September 25, 2012 |
MipTec 2012 - DiscoveRx Technology Symposium
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| September 24, 2012 |
MipTec 2012
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| September 20, 2012 |
Eurpoean DiscoveRx Technology Symposium - Cambridge
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| September 18, 2012 |
European DiscoveRx Technology Symposium - Born
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| September 12, 2012 |
DiscoveRx Technology Symposium - San Diego
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| June 19, 2012 |
SLAS Asia 2012
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| June 4, 2012 |
CHI - Next Gen Kinase Inhibitors
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| May 30, 2012 |
7th Protein Kinases In Drug Discovery
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| May 8, 2012 |
16th Annual Merck Technology Symposium Exhibitor Site
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| April 30, 2012 |
Eighth Annual PEGS
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Society for Laboratory Automation & Screening 2017
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IMMUNOLOGY 2017
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CASSS Bioassays 2017
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