Consider Eurofins DiscoverX’s custom development capabilities for custom cell lines, assays, & enzyme development.
Eurofins DiscoverX® detection kits were developed in tandem with our vast offering of cell lines and their differing MOAs and targets for a sensitive, quantitative readout of your therapeutic molecule. Whether your therapeutic is a biologic, peptide, a small molecule, or a cell therapy, these detection kits provide accurate pharmacology and reproducible results. Choose from various detection kits and reagents with chemiluminescent and fluorescent readouts to suit the diverse needs of your drug discovery and development programs.
The homogeneous, one-step addition detection kit protocols are easy-to-run and scalable for 96 well formats through high-throughput screening (HTS) of 384, 1536, or 3456 assay formats. They include options for running in agonist, antagonist, inverse agonist, and allosteric modulator modes. When used in conjunction with Eurofins DiscoverX cell lines, the detection kits are fully optimized for identifying various assayable events, such as detecting cell-based protein-protein interactions, compound-protein binding, cell death, translocation, and more.
Eurofins DiscoverX has over two decades of experience developing and optimizing detection kits and reagents to support our engineered cell lines. Utilize Eurofins DiscoverX’s optimized detection kits and reagents with PathHunter®, KILR®, cAMP Hunter™, and InCELL cell lines for highly sensitive and reproducible results you can rely on.
Consider Eurofins DiscoverX’s custom development capabilities for custom cell lines, assays, & enzyme development.
Choose from various detection kits and reagents with chemiluminescent and fluorescent readouts to suit the diverse needs of your drug discovery and development programs. Visit Instrument Compatibility for luminescence and fluorescent assays compatible instruments.
Detection kits are based on the proprietary Enzyme Fragment Complementation (EFC) technology designed for PathHunter, KILR, cAMP Hunter, and InCELL cell lines. These kits allow for the detection of complementation of the EFC β-galactosidase (β-gal) large enzyme acceptor (EA) and small enzyme donor (ED; also called ProLabel® (PK) or ProLink™ (ePL) fragments.
Fluorescent readout kits and reagents to measure intracellular calcium mobilization in GPCR Gq-coupled cell lines and Ion Channel cells or monitor ATP depletion and ADP production in cells for kinase profiling applications.
Chemiluminescent kit to help confirm EFC β-galactosidase large enzyme acceptor (EA) or small enzyme donor (ED) ProLink- and ProLabel-tagged protein expression within Eurofins DiscoverX cell lines