Screen for novel kinase inhibitors
Study kinase binding & pathways
Perform pharmacological profiling
Evaluate kinase receptor activation from therapeutic binding through downstream translocation
Measure RTK receptor dimerization, phosphorylation, internalization, & SH2-recruitment
Determine compound membrane penetration & kinase target binding
Analyze kinase activity & ADP accumulation |
Homogeneous assays with easy-to-use, rapid, no-wash protocols
Biologically relevant functional cell-based, MOA-reflective assays from discovery, through development, to QC lot release testing
Luminescent & fluorescent read-outs
Large recombinant kinase portfolio with broad coverage of human Kinome
Rigorous quality control & highly reproducible products (lot-to-lot) |
Stable cell lines
Ready-to-use eXpress & bioassay kits
Biologically relevant functional cell-based, MOA-reflective assays
Cell-based binding assays
Active, inactive, unactive, & mutant recombinant kinase enzymes
Kinase activity ADP accumulation kits
Custom product development |
Implemented in numerous biologics lot release programs globally
The original kinase company as part of Millipore / Upstate Biotechnologies
Assays, cell lines, enzymes, & assay platforms run by Eurofins Discovery KinaseProfiler & CRO screens daily
Helpful & experience customer support |